چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | امیررضا جهانشاهی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده پزشکی |
| کد مقاله | 79551 |
| عنوان فارسی مقاله | پارکینسونیسم |
| عنوان لاتین مقاله | PARKINSONISM |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | سی و هفتمین کنگره رادیولوژی ایران |
| نوع کنگره / همایش | ملی |
| کشور محل برگزاری کنگره/ همایش | Iran (Islamic Republic) |
| شهر محل برگزاری کنگره/ همایش | tehran |
| سال انتشار/ ارائه شمسی | 1401 |
| سال انتشار/ارائه میلادی | 2022 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1401/04/28 الی 1401/04/31 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://37.icrad.ir/paper-submission |
| آدرس علمی (Affiliation) نویسنده متقاضی | professor of radiology, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran |
| نویسنده | نفر چندم مقاله |
|---|---|
| امیررضا جهانشاهی | اول |
| عنوان | متن |
|---|---|
| کلمات کلیدی | Parkinson’s disease-MRI |
| خلاصه مقاله | Most patients (about 80–85%) diagnosed with Parkinson’s disease have what is called primary parkinsonism or idiopathic Parkinson’s disease (meaning that the disease has no known cause). This type tends to respond well to drugs that work by increasing or substituting dopamine molecules in the brain but at secondary parkinsonism type ,a key difference is that patients do not respond well to dopaminergic medications such as levodopa and second type Includes drug-induced parkinsonism, vascular parkinsonism, normal pressure hydrocephalus (NSA), corticobasal degeneration (CBD),progressive supranuclear palsy (PSP) and also multiple system atrophy (MSA). Progressive supranuclear palsy (PSP) is more common forms of secondary parkinsonism. As with idiopathic Parkinson’s disease, progressive supranuclear palsy has a late age of onset, but the symptoms tend to progress far more rapidly once they appear. However, dementia tends to have a later onset as the disease progresses. Multiple system atrophy (MSA)results in symptoms that are similar to idiopathic Parkinson’s disease, but with a much faster progression. Corticobasal degeneration (CBD) is the least common of the atypical parkinsonisms and caused by a buildup of proteins called tau, which damage parts of the brain. In most cases the diagnosis of probable PD can be made on clinical grounds, and no ancillary investigations are needed, however, in early PD the full triad of clinical symptoms and signs (bradykinesia, tremor at rest and rigidity) may not yet be manifested Substancia nigra is located at midbrain and composed from pars compacta and retinacula. Pars compacta is formed by dopaminergic neurons and located medial to pars reticulata (between this part and red nucleus) CT scans can show nonspecific atrophy with enlarged ventricles and sulci and Conventional MRI at 1.5 T with routine T2- and T1W imaging does not reveal disease-specific abnormalities in PD and, particularly in the early phases, the MRI appears normal and Its main role is to exclude 1.subcortical vascular pathology, 2.rare secondary causes of parkinsonism (e.g., Wilson’s disease, NPH, or tumors, granulomas, or calcification of basal ganglia), and 3.in discriminating atypical parkinsonian syndromes. T1 images may show mild hyperintensity of compact and reticular parts of the substantia nigra and red nuclei (due to iron accumulation) or may show loss of normal slight hyperintensity in substantia nigra due to loss of neuromelanin. Loss of the normal swallow tail appearance of susceptibility signal pattern in the substantia nigra on axial imaging is perhaps the most promising diagnostic sign and swallow tail sign describes the normal axial imaging appearance of nigrosome-1 within the substantia nigra on high-resolution T2*/ SWI weighted MRI. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Parkinsonism.JPG | 1401/06/14 | 175647 | دانلود |
| Parkinsonism.JPG | 1401/06/14 | 175647 | دانلود |
| parkinsonism govahi.JPG | 1401/06/14 | 69025 | دانلود |
| abstract book 1401.JPG | 1401/06/14 | 81370 | دانلود |
