| خلاصه مقاله | Introduction: Microbial agents producing abscesses in the skin, viscera and soft tissues include various types of aerobic and non- aerobic bacteria. The most important are Staphylococcus aureus, streptococcus, Escherichia coli, Pseudomonas, Bacteroides and klebsiella. The main treatment of abscess, pushing out through drainage or split abscess. After removing the necrotic tissue and pus, The antibiotic should be used to treat the disease. The aim of this study was to determine the aerosol production of abscess in skin, viscera and soft tissue and then to evaluate their susceptibility to different antibiotics.
Material and methods: Specimens of bacterial isolated from skin abscesses and infections and other connective tissue components that were identified, cultured and antibiogram into the microbiological laboratory of the Tabriz children center were extracted and then clinical information was obtained from patients. The data included the age, sex, location of the infection ,its association with hospital infections (in case of suspicion of nosocomial infections) and the manner of intervention, including aspiration,surgical drainage,or of type of antibiotic therapy.
Results: clinical and laboratory data of patients with skin and soft tissue admitted to Tabriz children’s hospital. 100 samples of positive blood culture were selected during 5 years and used for evaluation of drug resistance pattern. In this study 52.3 % of the patients were males and 47.7% were females. Of the 100 positive culture cases ,47.7% were Staphylococcus aureus ,8% Klebsiella and 8% Esherichia coli .46.6% of cases included soft tissue abscesses,33% of visceral absesses and 20.5 % of skin abcesses, The results of the antibiogram showed that Staphylococcus aureus versus penicillin was 79.5% oxacillin34.1% ,amikacin 26.2% clindamycin ,29.3% erythromycin,35%cefalexin,12.5% ceftizoxime and ceftriaxone 22% and Vancomycine 2.4% are resistant
Conclusion: The susceptibility and resistance pattern of Staphylococcus aureus is unpredictable and multiple resistance is common .At present resistance to Vancomycin is low ,of course. This level of resistance should be confirmed by more precise methods such as MIC or E test measurements. Obviously .the use of Vancomycine should be limited to the treatment of serious infectious disease and in cases of non critical infectious disease acquired by the community Antibiotics such as cephalexin and clindamycin can still be used .In this study ,high levels of resistance to penicillin are also evident. |