| خلاصه مقاله | Zeolites are crystalline microporous materials consisting of SiO4 and AlO4 with a wide range of applications in environmental protection, industry, and medicine. The porous structure of zeolites provides the possibility of their use as support for iron oxide nanoparticles in magnetic resonance imaging (MRI) [1-3]. The present study aimed to evaluate the effect of Gd2O3/ZSM-5 nanocomposite on water protons relaxation rate. Gd2O3/ZSM-5 nanocomposite was synthesized by hydrothermal method [4]. The XRD, SEM, and VSM tests were carried out to determine the structure, morphology and size, and magnetic property of the nanocomposite, respectively. Besides, an MTT assay was used to consider the effect of the nanocomposite on the cell viability, and MRI was performed to investigate the relationship between the 1/T1 relaxation rate and Gd3+ concentration of the nanocomposite. The nanocomposite showed a spherical shape, paramagnetic property, cytocompatibility, and linear changes of the water protons relaxation rate with Gd3+ concentration. The change of water protons relaxation rate using Gd2O3/ZSM-5 nanocomposite suggests the effective role of ZSM-5 support in contrast enhancement of the MRI images. |