| خلاصه مقاله | Up to two thirds of standard recordings show no epileptiform activity (only focal slowing or no abnormalities).
When present, the epileptiform discharges can be unilateral or bilateral (The interictal epileptiform activity is typically bilateral, even in patients with unilateral seizures, but typically one side has a preponderance).
Sleep activates independent interictal epileptiform discharges (IED). Waking and REM restrict IED to primary focus. Sleep deprivation can often activate focal epileptiform discharges; therefore, an EEG with sleep recording is recommended during the diagnostic workup.
The presence of mid or posterior temporal spikes may suggest a more widespread epileptogenic network even in the presence of clear mesial temporal pathology.
Temporal intermittent rhythmic delta activity (TIRDA) has a strong association with epileptiform discharges.
The use of anterior temporal electrodes (T1, T2) or invasive sphenoidal electrodes can increase the sensitivity for the detection of mesial temporal epileptiform discharges .
Interictal EEG features can help to distinguishing mesial and lateral temporal lobe epilepsy . In Mesial TLE,IEDs predominantly over the ipsilateral mesial temporal regions ( F7/F8,T1/T2,SP1/2 or FT9/10 ) and TIRDAs are more likely .But in Lateral (Neocortical or Perisylvian foci ) TLE, IEDs are with lateral neocortical (mid to posterior temporal ) predominance ( T7/T8 ie T3/T4; P7/P8 ie T5/T6 ). |