استفاده از اگزوزوم برای تعدیل آسیب های ناشی از بیماری کووید-19
Application of exosomes for the alleviation of COVID-19-related pathologies
نویسندگان: آیسا رضابخش , مهدی مهدی پور , پریا حبیب الهی , رضا رهبرقاضی
کلمات کلیدی: COVID‐19, exosomes, paracrine interaction, regenerative potential, stem cell, therapeuticeffects
نشریه: 6321 , 5 , 40 , 2022
| نویسنده ثبت کننده مقاله |
رضا رهبرقاضی |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز سلولهای بنیادی |
| کد مقاله |
79200 |
| عنوان فارسی مقاله |
استفاده از اگزوزوم برای تعدیل آسیب های ناشی از بیماری کووید-19 |
| عنوان لاتین مقاله |
Application of exosomes for the alleviation of COVID-19-related pathologies |
| ناشر |
7 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Review Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| The pandemic of COVID-19 caused worldwide concern. Due to the lack of appropriate medications and the inefficiency of commercially available vaccines, lots of efforts are being made to develop de novo therapeutic modalities. Besides this, the possibility of several genetic mutations in the viral genome has led to the generation of resistant strains such as Omicron against neutralizing antibodies and vaccines, leading to worsening public health status. Exosomes (Exo), nanosized vesicles, possess several therapeutic properties that participate in intercellular communication. The discovery and application of Exo in regenerative medicine have paved the way for the alleviation of several pathologies. These nanosized particles act as natural bioshuttles and transfer several biomolecules and anti-inflammatory cytokines. To date, several approaches are available for the administration of Exo into the targeted site inside the body, although the establishment of standard administration routes remains unclear. As severe acute respiratory syndrome coronavirus 2 primarily affects the respiratory system, we here tried to highlight the transplantation of Exo in the alleviation of COVID-19 pathologies. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| 17413905.pdf | 1401/05/04 | 1541496 | دانلود |