چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Exhaled breath condensate (EBC) is used to investigate the efficacy of EBC to detect the genetic mutations in patients with lung cancer. Samples of 5 patients and 5 healthy volunteers were collected. DNA was extracted and used for amplification of hotspot regions of TP53 and KRAS genes by using PCR. We performed the mutation analysis by direct sequencing in all subjects. Detected mutations in EBC samples were compared with those of corresponding tumor tissues and there was complete agreement within the detected mutations in EBC and tumorous tissue. EBC can be used as an efficient and noninvasive source for the assessment of gene mutations in patients with lung cancer. |
| نویسنده | نفر چندم مقاله |
|---|---|
| ابوالقاسم جویبان | ششم |
| سمیه کاظمی نسب | اول |
| بابک امامعلی زاده | سوم |
| وحید جویبان قراملکی | چهارم |
| علی تقی زادیه | پنجم |
| مریم خوب نسب جعفری | هفتم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Nucleosides Nucleotides and Nucleic acids 41 (2022) 370-383.pdf | 1401/04/14 | 1937758 | دانلود |
