چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| مریم رف رف | دوم |
| فاطمه پورحبیبی | اول |
| علی اصغر ابراهیمی چهارم | پنجم |
| محمد اصغری جعفرآبادی | چهارم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Rheumatoid arthritis (RA) is a chronic autoimmune and inflammatory disease that leads to joints damage accompanied by several extra-articular problems, including cardiovascular disease. This study aimed to investigate the effects of curcumin supplementation on metabolic parameters (glycemic indices and lipid profile) in women with RA. Methods: In this randomized, double-blind , placebo-controlled clinical trial, 48 women with RA were treated with curcumin (500 mg once a day) or placebo for 8 weeks. Fasting blood sugar (FBS), insulin, homeostatic model assessment in insulin resistance (HOMA-IR), and lipid profile of subjects were measured at baseline and the end of the study. Results: There was a significant decrease in HOMA-IR and serum levels of triglycerides in the curcumin group compared with the placebo at the end of the study (P<0.05 for all). HOMA-IR and triglyceride levels significantly increased within the placebo group. Changes in FBS, insulin, and other lipids profile levels were not significant in any of the groups (P>0.05). Conclusion: According to these results, consumption of curcumin, as a part of an integrated approach, can modulate metabolic factors in women with RA. |
| کلمات کلیدی | curcumin; metabolic parameters ; rheumatoid arthritis |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Mahhad 1401 congress(1).pdf | 1401/05/12 | 11189039 | دانلود |
| Metabolic Abstract.pdf | 1401/05/12 | 290461 | دانلود |
| CamScanner 08-03-2022 09.01.43.pdf | 1401/05/12 | 330186 | دانلود |
