Chitosan-based biomaterials for the treatment of bone disorders

Chitosan-based biomaterials for the treatment of bone disorders


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نویسندگان: جعفر سلیمانی

کلمات کلیدی: Natural polymers Polysaccharides Bone-related disease Chitosan Biomedical applications

نشریه: 15044 , 2022 , 215 , 2022

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نویسنده ثبت کننده مقاله جعفر سلیمانی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات آنالیز دارویی
کد مقاله 78958
عنوان فارسی مقاله Chitosan-based biomaterials for the treatment of bone disorders
عنوان لاتین مقاله Chitosan-based biomaterials for the treatment of bone disorders
ناشر 8
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Review Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Bone is an alive and dynamic organ that is well-differentiated and originated from mesenchymal tissues. Bone undergoes continuous remodeling during the lifetime of an individual. Although knowledge regarding bones and their disorders has been constantly growing, much attention has been devoted to effective treatments that can be used, both from materials and medical performance points of view. Polymers derived from natural sources, for example polysaccharides, are generally biocompatible and are therefore considered excellent candidates for various biomedical applications. This review outlines the development of chitosan-based biomaterials for the treatment of bone disorders including bone fracture, osteoporosis, osteoarthritis, arthritis rheumatoid, and osteosarcoma. Different examples of chitosan-based formulations in the form of gels, micro/nanoparticles, and films are discussed herein. The work also reviews recent patents and important developments related to the use of chitosan in the treatment of bone disorders. Although most of the cited research was accomplished before reaching the clinical application level, this manuscript summarizes the latest achievements within chitosan-based biomaterials used for the treatment of bone disorders and provides perspectives for future scientific activities.

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جعفر سلیمانیهفتم

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10-Chitosan-Bone.pdf1401/04/024065307دانلود