| ct
Background: Red cell distribution width (RDW) is a parameter that indsicates the heterogeneity of red blood cell size
and could be a prognostic factor in some diseases. Also, intracerebral hemorrhage (ICH) is considered a vascular event
with a high mortality rate. We aimed to examine the role of RDW, neutrophil to lymphocyte ratio (NLR), and neutrophil
to platelet ratio (NPR) in predicting the prognosis of patients with ICH.
Methods: This is a retrospective cohort study conducted on 140 patients with ICH admitted to the neurology ward
and intensive care unit (ICU) in Imam Reza Hospital, Tabriz, Iran. Demographic data, National Institutes of Health Stroke
Scale (NIHSS), and complete blood count test parameters were evaluated within 24 h after hospitalization. These variables were collected and re-evaluated three months later.
Results: The mean age of the study population was 61.14 (±16) years and 51% were male. The mean NLR (p=0.05),
neutrophil count (p=0.04), platelet count (p=0.05), and NIHSS (p<0.01) had a signifcant diference between the
deceased patients and those who partially recovered after three months. The ROC curve showed that NIHSS (area
under curve (AUC): 0.902), followed by NPR (AUC: 0.682) variables had the highest AUC.
Conclusion: RDW could be a relevant prognostic factor and predictor in determining 3-months survival in ICH. Nevertheless, further large-scale prospective cohorts might be needed to evaluate the associations.
Keywords: Red cell distribution width, Intracerebral hemorrhage, Neutrophil to lymphocyte ratio, Neutrophil to
platelet ratio, Prognosis |