| In recent years, the number of cases of extrapulmonary tuberculosis
in Iran has increased. The goal of this study was to determine the
epidemiological status, clinical symptoms, diagnostic methods, and
treatment strategies of extrapulmonary tuberculosis in Iran, with a
focus on tuberculosis meningitis and miliary tuberculosis. Between
January 1, 2000 and June 1, 2021, 1 651 cases of tuberculosis
meningitis and miliary tuberculosis were discovered in Iran. The
prevalence of tuberculosis meningitis was higher in Sistan and
Baluchestan, South Khorasan, and Mazandaran compared with
other provinces. The most prevalent symptoms of tuberculous
meningitis were fever, anorexia, headache, neck stiffness, loss of
consciousness, and vomiting. The most commonly used procedures
for diagnosing tuberculous meningitis were polymerase chain
reaction and cerebrospinal fluid culture. The most prevalent clinical
symptoms of miliary tuberculosis were fever, lethargy, weariness,
and anorexia. In 70% of chest radiographs, a miliary pattern
was visible. Bone marrow biopsy was used to diagnose miliary
tuberculosis in 80% of patients, while bronchoalveolar lavage was
used in 20% of cases. The conventional 6-month treatment approach
for tuberculous meningitis and miliary tuberculosis was used for all
of the participants in the investigations. Given the high prevalence
of extrapulmonary tuberculosis patients in Iran and the devastating
consequences of the disease, the researchers recommend that further
study be done to prevent extrapulmonary tuberculosis in the general
population. |