| Introduction:
Coronavirus Disease in 2019 (COVID-19) is globally
a major factor in the mortality of patients. Hence, there is an
immediate requirement to recognise the mortality predictors in
the COVID-19 patients.
Aim:
To identify the clinical features and risk factors for the
mortality of adult patients suffering from COVID-19 in Sirjan, Iran.
Materials and Methods:
In this retrospective cohort study, all
demographic, clinical, laboratory data of COVID-19 patients who
were admitted to hospitals of Sirjan city was collected from July
to October 2020 and data was analysed in November 2020. In this
period, 269 patients with COVID-19 were admitted. The findings
based on the considered parameters of patients in the hospital
was recorded; Univariable and multivariable logistic regression
methods were applied to find the risk factors due to in hospital
death.
Results:
Out of 269 patients, 39 patients (14.5%) died in the
hospital and the rest were discharged. A total of 152 (56.5%)
patients had co-morbidity. Hypertension (HTN) was the most
common underlying disease 71 (26.4%), followed by Diabetes
Mellitus (DM) 55 (20.4%), cardiac disease, and Chronic
Obstructive Pulmonary Disorder (COPD). The most common
symptom was dyspnea 207 (77%), coughing and fever. The most
common findings in the chest Computed Tomography (CT) scan
of patients was ground-glass opacity with a frequency of 150
among 188 patients (79.8%) in patients with the abnormal CT
scan. Multivariable regression indicated the increased odds of in
hospital death associated with COPD (OR=3.20, 95% CI 1.02–
10.04; p=0.046), arterial saturation of oxygen
≤
93% (OR=5.70,
95% CL 2.42–13.40; p<0.001), and leukocytosis (OR=7.26, 95%
CL, 3.02-17.49, p<0.001).
Conclusion:
Based on the results of the present study, COPD,
arterial saturation of oxygen (
≤
93%), and leukocytosis were risk
factors for the hospital mortality of COVID-19. It might be proper
for the initial determination of patients who may need life saving
interventions |