Nanoliposomal co-encapsulation of cinnamon extract and zein hydrolysates with synergistic antioxidant activity for nutraceutical applications

Nanoliposomal co-encapsulation of cinnamon extract and zein hydrolysates with synergistic antioxidant activity for nutraceutical applications


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دانشگاه علوم پزشکی تبریز
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نویسندگان: مهناز طبیبی اذر , حامد همیشه کار

کلمات کلیدی: Antioxidant activity · Encapsulation efficiency · Protein hydrolysates · Hydrolysis degree

نشریه: 6564 , 2022 , 76 , 2022

اطلاعات کلی مقاله
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نویسنده ثبت کننده مقاله مهناز طبیبی اذر
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده تغذیه
کد مقاله 78668
عنوان فارسی مقاله Nanoliposomal co-encapsulation of cinnamon extract and zein hydrolysates with synergistic antioxidant activity for nutraceutical applications
عنوان لاتین مقاله Nanoliposomal co-encapsulation of cinnamon extract and zein hydrolysates with synergistic antioxidant activity for nutraceutical applications
ناشر 5
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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The present study aimed to co-encapsulate cinnamon extract (CE) and zein hydrolysate (ZH) with nanoliposomes (NLPs). The CE and ZH were successfully loaded in NLPs with 94.25 ± 7.13% and 92.36 ± 3.22% of encapsulation efficiency, respectively. The NLPs were co-loaded with CE and ZH and showed high α-diphenyl-β-picrylhydrazyl (DPPH) scavenging activity (63.38 ± 4.16%) on account of the synergistic antioxidative relation between CE and ZH. This synergistic antioxidative significantly decreased the thiobarbituric acid-reactive substances in the oxidized NLPs co-loaded with CE and ZH. The particle size of the produced NLP samples was lower than 100 nm, and the co-loading of CE and ZH significantly decreased the particle size in the oxidized NLPs. Moreover, the formation of electrostatic interactions between the loaded compounds and liposome interfacial membrane was approved by the changes in zeta potential when loading CE and ZH. The morphology study exhibited that the co-loading of CE and ZH significantly decreased the oxidative damages and particle size of NLPs. In conclusion, the NLPs co-loaded with CE and ZH were potentially efficient candidates to be applied as natural antioxidants in food industry.

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نویسنده نفر چندم مقاله
مهناز طبیبی اذرسوم
حامد همیشه کارچهارم

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