چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| In this study, a fluorometric probe based on luminol-terbium coordination polymer nanoparticles (luminol-Tb CP NPs) is validated for the quantification of phenobarbital in the exhaled breath condensate collected from expiratory circuit of the mechanical ventilator (MVEBC). It relies on the coordination of phenobarbital to luminol-Tb CP NPs which casing an aggregation-induced fluorescence enhancement of probe owing to the increasing the system rigidity and the decreasing the nonradiative decay rate. As the increase in response intensity is proportional to phenobarbital amount, a method is offered for its determination in MVEBC. This method presents a linear relationship with phenobarbital concentration in the range of 0.1–10.0 mg.L−1 with a limit of detection of 0.024 mg.L−1 and the relative standard deviation of 3.6%. The proposed method is used in MVEBC of the pre-term newborn babies receiving phenobarbital under mechanical ventilator. |
| نویسنده | نفر چندم مقاله |
|---|---|
| مهدی مختاری | اول |
| الهه رحیم پور | دوم |
| وحید جویبان قراملکی | سوم |
| مریم خوب نسب جعفری | چهارم |
| محمدباقر حسینی | پنجم |
| ابوالقاسم جویبان | ششم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Development a coordination polymer based nanosensor for phenobarbital.pdf | 1401/01/27 | 2462776 | دانلود |
