Loss of Consciousness and Seizure in Patient with Tricyclic Antidepressant Poisoning and with Atypical ECG Changes

Loss of Consciousness and Seizure in Patient with Tricyclic Antidepressant Poisoning and with Atypical ECG Changes


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نویسندگان: کاووس شهسواری نیا , افشین قره خانی , ندا گیلانی

کلمات کلیدی: Tricyclic Antidepressants; Electrocardiography; Left Bundle Branch Block; Suicide

نشریه: 0 , 1 , 6 , 2021

اطلاعات کلی مقاله
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نویسنده ثبت کننده مقاله ندا گیلانی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده بهداشت
کد مقاله 78457
عنوان فارسی مقاله Loss of Consciousness and Seizure in Patient with Tricyclic Antidepressant Poisoning and with Atypical ECG Changes
عنوان لاتین مقاله Loss of Consciousness and Seizure in Patient with Tricyclic Antidepressant Poisoning and with Atypical ECG Changes
ناشر 4
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق) Journal of Medical Physiology
نوع مقاله Case Report
نحوه ایندکس شدن مقاله ایندکس شده سطح چهار – SID/Iranmedex/Magiran
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Antidepressants can be abused for committing suicide despite effectiveness in treatment of depression. Tricyclic Antidepressants (TCA) were considered the first line of treatment for depression. A 23-year-old woman brought to emergency department by EMS personnel due to convulsion and loss of consciousness. She had taken 90 of pills (Amitriptyline 75 mg) at once to commit suicide. The patient was intubated and connected to the mechanical ventilator and admitted to the women’s toxicity ICU. Over 48-72-hour hospitalization, ECG changes persistent. In this case, ECG changes were in the form of LBBB over view with wide QRS (160 msec) and long QTC (520 msec). But, the R/S ratio above 0.7 and RAD was not observed in patient’s ECG. In the 4th hospitalization day, QRS waves began to narrow, and on the 5th day, the patient’s ECG returned to normal completely. In drug poisonings, there are a series of clinical and paraclinical manifestations that can help in the diagnosis of patient. Management of patients should not only rely on clinical or para-clinical sings . In TCA poisoning, ECG changes have no single pattern and can lead to a variety of changes and can also persist for days after poisoning despite the clinical recovery.

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نویسنده نفر چندم مقاله
کاووس شهسواری نیااول
افشین قره خانیدوم
ندا گیلانیچهارم

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64-227-1-PB (1).pdf1401/01/17640722دانلود