چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Kidney diseases have recently become one of the major global health problems with high incidence and death risk. Extracellular vesicles (EVs), which are detectable in most of cell types and human body fluids, have recently attracted extensive attention as the main carriers of protective cargos such as microRNAs and proteins that may contribute to promoted renal function. Therefore, we conducted this systematic review to investigate the renoprotective potential of EVs. We performed a comprehensive search of Medline (via PubMed), Embase, Cochrane and Proquest on August 2019 for English papers. Of 2887 articles met the search criteria, 80 included in this systematic review and classified into several groups based on source of EVs. We then evaluated the EV research through screening their isolation method, size, marker, main effector, and potential mechanisms to induce renal protection. Taken together, EVs from various sources except some tubular epithelial cells, fibroblasts, platelets, and podocyte might have positive impacts on treatment of human kidney diseases in the future. |
| نویسنده | نفر چندم مقاله |
|---|---|
| فرزانه قربانی | اول |
| علی اکبر موثق پور اکبری | دوم |
| مهدی طالبی | سوم |
| مهدی یوسفی | چهارم |
| حسین عباس زاده | پنجم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Systematic.pdf | 1400/12/17 | 1078542 | دانلود |
