| خلاصه مقاله | Background: Cardiovascular disease (CVD) is the leading cause of mortality among men and women around the world. The aim of this study was to investigate lipid profile and oxidized low density lipoprotein cholesterol (ox-LDL) as cardiovascular risk factors in women living in the Tabriz petrochemical region, Iran.
Methods: In this cross-sectional study, a sample of 152 women aged 30-55 years was selected from who attended health center in Tabriz and Fasting serum lipid profile and ox-LDL were evaluated.
Results: High serum triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and low high-density lipoprotein cholesterol (HDL-C) were determined in 32.5%, 25.7%, 17.8% and 56.6% of subjects, respectively. The median of serum ox-LDL concentration was 3181.5 ng/L. In the multiple-adjusted quintile regression analysis, significant relationships were found between serum ox-LDL and age (B = 96.7, P = 0.003).
Conclusion: The high prevalence of high serum TG and low HDL-C as cardiovascular risk factors in the studied women warrants more public health attention. The findings also suggest that aging was associated with high serum ox-LDL that confirms in aging and age-related metabolic disorders such as dyslipidemia, hyperglycemia, insulin resistance and metabolic syndrome enhancement of oxidative stress and superoxide |