چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Favipiravir is one of the most commonly prescribed drugs in the treatment of COVID-19 in the early stages of the disease. In this work, the solubility of favipiravir was measured in supercritical CO2 at temperatures ranging from 308 to 338 K and pressures ranging from 12 to 30 MPa. The mole fraction solubility of favipiravir was in the range of 3.0 × 10-6 to 9.05 × 10-4. The solubility data were correlated with three types of methods including; (a) density-based models (Chrastil, Garlapati and Madras, Sparks et al., Sodeifan et al., K-J and Keshmiri et al.), (b) Equations of states SRK with quadratic mixing rules) and (c) expanded liquid theory (modifed Wilson model). According to the results, modifed Wilson and K-J models are generally capable of providing good correlation of solubility. Finally, the approximate values of total (ΔHtotal), vaporization (ΔHvap), and solvation (ΔHsol) enthalpies were computed. |
| نویسنده | نفر چندم مقاله |
|---|---|
| ابوالقاسم جویبان | پنجم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| J Supercritic Fluids 183 (2022) 105539.pdf | 1400/12/15 | 2941711 | دانلود |
