چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Abstract Aims: Skin cancer is the most widespread cancer worldwide, mainly caused by exposure to ultraviolet radiation (UV) in sunlight. Utilizing topical preventive agents in routinely daily used cosmetics may prevent UV-related skin damages and skin cancers. γ-Oryzanol (GO) is a natural component derived from rice bran oil, with potential antioxidant and skin anti-aging properties. Main methods: We biologically thorough studied the antioxidant and anticancer effects of GO in vitro to found the effective signaling pathways, then evaluated the sun protection factor of prepared formulation, and finally investigated the long-term preventive effects of GO-loaded nanoethosomes (GO-NEs) against UVB-induced skin cancer in mice. Key findings: GO-NEs could effectively prevent UVB-induced skin cancer. Significance: Our results suggest that GO-NEs could be utilized as an innovative ingredient in cosmetics. |
| نویسنده | نفر چندم مقاله |
|---|---|
| حسین بابائی | پنجم |
| حامد همیشه کار | هفتم |
| مهدی زینالی | اول |
| سهیل عباس پوررواسجانی | دوم |
| طناز سلطان فام | سوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Prevention-of-UV-induced-skin-cancer-in-mice-by-gamma-oryzano_2021_Life-Scie.pdf | 1400/12/04 | 24976038 | دانلود |
