| Newly, the usage of nanofbers (NFs) as wound dressings with the aim of their rapid healing and prevention of bacterial
infection has been considered by researchers. In this regard, we produced the ethylcellulose/hydroxypropyl methylcellulose
NFs incorporated with Aloe-vera (EC/HPMC/Alv) by the electrospinning technique. The produced NFs were investigated
for their chemical structure, morphological, mechanical, degradation, swelling, cell viability, and antibacterial properties.
Amongst the produced NFs, the NF samples containing 10% Alv illustrated the appropriate mechanical properties. The
produced NFs did not show any cell cytotoxicity which indicates their good compatibility. Also, NFs containing Alv signifcantly (P < 0.05) increased cell proliferation and adhesion. In addition, the NFs/Alv sample was indicated antibacterial
ability against Staphylococcus aureus (10.21 ± 1.21 mm) and Escherichia coli (5.06 ± 1.3 mm) pathogenic bacteria. As a
result, these fndings suggest that the produced NFs could be applied as an active mat for wound dressing application. |