چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | مهین آهنگر اسکوئی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده پزشکی |
| کد مقاله | 78097 |
| عنوان فارسی مقاله | Detection of Epstein–Barr Virus in among women breast cancer in Tabriz |
| عنوان لاتین مقاله | Detection of Epstein–Barr Virus in among women breast cancer in Tabriz |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | سیزدهمین کنگره بین الملی آزمایشگاه و بالین |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | Iran (Islamic Republic) |
| شهر محل برگزاری کنگره/ همایش | تهران |
| سال انتشار/ ارائه شمسی | 1400 |
| سال انتشار/ارائه میلادی | 2022 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1400/11/16 الی 1400/11/20 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://congressapp.ir/isacl2022/index.php |
| آدرس علمی (Affiliation) نویسنده متقاضی | Department of Microbiology & Virology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. 2. Infectious and Tropical Diseases Research Center, Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. |
| نویسنده | نفر چندم مقاله |
|---|---|
| مهین آهنگر اسکوئی | اول |
| آرزو آزادی | سوم |
| رعنا فرضی | چهارم |
| فربد علی نژاد | دوم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Abstract: Background and Aim: After cervical cancer, breast cancer is the most common type of cancer among women. The cause of this cancer has not yet been fully identified, and several factors, including various environmental factors, including infectious agents, may play a role.. The role of viruses in breast cancer has not yet been well established, however, studies of the association and the presence of EBV in breast cancer, have had inconsistent, from 0% to 50%. The aim of this study, was investigating the EBV EBER gene in paraffin sample women with and without breast cancer in Tabriz. Material & Method: In our study, we collected 80 paraffin-embedded malignant breast cancer tissue samples and 80 samples with non-cancerous tissues from the pathology lab in Tabriz. Deparaffinization and DNA extraction was performed using protocol mentioned in previous studies (2) . The EBER region of the EBV genome was used as the primer for the detection of EBV in all samples by PCR (4). Results: In our study, EBER gene of EBV was detected in 11.2% (9 out of 80) of breast cancer tissues and none in the non-cancerous tissues. The highest frequency of EBV – EBER in breast cancer samples was observed in Invasive Ductal Carcinoma II (10.9%) and in ≤ 50 age group (13.2%). Conclusion: Basie of our finding, our results showed a possible role of EBV infection in breast cancer in Tabriz. These patients probably are infected with EBV at an early age, that the virus remains in their bodies, and that it may have contributed to cancer progression . Additionally, the exact mechanism of the potential role of EBV in breast cancer is yet to be elucidated. |
| کلمات کلیدی | EBV, Breast cancer, Invasive Ductal Carcinoma II |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| EBV in breast cancer.jpg | 1400/11/25 | 1213197 | دانلود |
| Certificate of participation.jpg | 1400/12/01 | 646734 | دانلود |
| Certificate of presentation.jpg | 1400/12/01 | 381558 | دانلود |
