چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | علی احمدعلی پور |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | روانپزشکی و علوم رفتاری |
| کد مقاله | 78018 |
| عنوان فارسی مقاله | رابطه بین پلی مورفیسم ها در سیستم اندوکانابینوئید و عملکردهای فیزیولوژیکی |
| عنوان لاتین مقاله | The relationship between polymorphisms in the endocannabinoid system and physiological functions |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | چهارمین کنگره بین المللی و بیست و پنجمین کنگره فیزیولوژی و فارماکولوژی |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | |
| شهر محل برگزاری کنگره/ همایش | تهران |
| سال انتشار/ ارائه شمسی | 1400 |
| سال انتشار/ارائه میلادی | 2021 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1400/07/28 الی 1400/07/30 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://cong25.phypha.ir/ |
| آدرس علمی (Affiliation) نویسنده متقاضی | Research Center of Psychiatry and Behavioral Sciences, Tabriz University of Medical Sciences, Tabriz, Iran. |
| نویسنده | نفر چندم مقاله |
|---|---|
| علی احمدعلی پور | دوم |
| لیلا حسین زاده انور | اول |
| فاطمه رضائیان فرح آبادی | سوم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | polymorphisms endocannabinoid system CB1 CB2 |
| خلاصه مقاله | Introduction: The endocannabinoid system is a biological system consisting of CB1 and CB2 receptors and about 15 different types of endogenous ligands including anandamide and 2-arachidonyl glycerol that target the receptors of this system. Other components of this system are enzymes including FAAH and MAGL, which are involved in the biosynthesis and inactivation of these endogenous ligands. CB1 receptors are found mainly in the terminals of central and peripheral neurons, where they usually inhibit the release of a wide range of different neurotransmitters. CB2 receptors are also located in immune cells that activating of this receptor can modulate the migration of immune cells and the release of cytokines into and out of the brain. Materials & Methods: This review article is the result of a review of research published in PubMed, Wiley, Science direct, ISI, Scopus, etc. between 2000 and 2021 about the relationship between the endocannabinoid system and physiological functions Results: Various studies have shown that this system is involved in many physiological processes including nociception (pain sensation), appetite, lipid metabolism, gastrointestinal motility, cardiovascular modulation, motor activity, and memory which can Become an emerging target for drug discovery. The involvement of the endocannabinoid system in most of these functional psychological and physiological processes is explained by its strong association with the dopaminergic system, mainly through the basal ganglia and corticolimbic brain structures. Conclusion: Various studies have linked FAAH and CB1 gene polymorphisms to various human diseases including obesity, systemic disorders, cardiovascular, lung, gastrointestinal diseases, and mental and neurological disorders including depression, bipolar disorder, and anxiety. Activity, schizophrenia, drug and alcohol addiction. This finding can make these genes as an effective therapeutic target. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 3.jpg | 1400/11/16 | 472394 | دانلود |
| hosseinzadeh.jpg | 1400/11/16 | 654595 | دانلود |
