چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Autoimmune diseases, especially among young people in the US, are one of the leading causes of morbidity and death. The immune responses are the fundamental pathogenicity of autoimmune disorders. The equilibrium between stimulatory and inhibitory signals is critical for the stimulation, migration, survival, and T cell-related immune responses. The B7 family can substantially regulate T cell-mediated immune responses. Nevertheless, recent breakthroughs in immune checkpoint blockade in cancer immunotherapy have facilitated autoimmune diseases, especially among the prone populations. In the current study, we tried to concisely review the role of the B7 family in regulating immune reactions and the influence of immune checkpoint inhibitors on autoimmunity development. |
| نویسنده | نفر چندم مقاله |
|---|---|
| نازیلا علیزاده قراملکی | دوم |
| مهدی عبدلی شادباد | چهارم |
| خلیل حاجی اصغرزاده | پنجم |
| لیلی عاقبتی | ششم |
| امیر باغبانزاده | هفتم |
| نگار حسین خانی | هشتم |
| نورا کریم آهنگر | نهم |
| بهزاد برادران | دهم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 598-B7 immune checkpoint family members as putative.pdf | 1400/10/28 | 1476297 | دانلود |
