چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Tumor-associated macrophages (TAMs) are among the abundant cell populations of the tumor microenvironment (TME), which have pivotal roles in tumor development, chemoresistance, immune evasion, and metastasis. Growing evidence indicates that TAMs and the cross-talk between TAMs and tumoral endothelial cells can substantially contribute to tumor angiogenesis, which is considered a vital process for cancer development. Besides, tumoral endothelial cells can regulate the leukocyte infiltration to the TME in solid cancers and contribute to immune evasion. Therefore, targeting the immunosuppressive TAMs and the cross-talk between them can be a promising strategy for improving anti-tumoral immune responses. This review aims to summarize the biology of TAMs, their recently identified roles in tumor development/angiogenesis, and recent advances in macrophage-based cancer immunotherapy approaches for treating cancers. |
| نویسنده | نفر چندم مقاله |
|---|---|
| زهرا اسدزاده | اول |
| نیما همت | سوم |
| امیر باغبانزاده | چهارم |
| مهدی عبدلی شادباد | پنجم |
| هاجر آل محمد | هشتم |
| مینا افراشته نور | نهم |
| بهزاد برادران | دوازدهم |
| ندا خسروی | ششم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| 594-The cross talk between tumor associated macrophages and tumor endothelium Recent advances in macrophage-based.pdf | 1400/10/27 | 3892199 | دانلود |
