CRISPR Technology in Gene-Editing-Based Detection and Treatment of SARS-CoV-2
CRISPR Technology in Gene-Editing-Based Detection and Treatment of SARS-CoV-2
نویسندگان: مهین آهنگر اسکوئی , علیرضا عیسی زاده
کلمات کلیدی: : coronaviruses, SARS-CoV-2, CRISPR/Cas9, gene editing, ACE-2 receptors
نشریه: 0 , 772788 , 8 , 2022
| نویسنده ثبت کننده مقاله |
مهین آهنگر اسکوئی |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشکده پزشکی |
| کد مقاله |
77830 |
| عنوان فارسی مقاله |
CRISPR Technology in Gene-Editing-Based Detection and Treatment of SARS-CoV-2 |
| عنوان لاتین مقاله |
CRISPR Technology in Gene-Editing-Based Detection and Treatment of SARS-CoV-2 |
| ناشر |
6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
Frontiers in Molecular Biosciences |
| نوع مقاله |
Review Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Outbreak and rapid spread of coronavirus disease (COVID-19) caused by coronavirus
acute respiratory syndrome (SARS-CoV-2) caused severe acute respiratory syndrome
(SARS-CoV-2) that started in Wuhan, and has become a global problem because of the
high rate of human-to-human transmission and severe respiratory infections. Because of
high prevalence of SARS-CoV-2, which threatens many people worldwide, rapid diagnosis
and simple treatment are needed. Genome editing is a nucleic acid-based approach to
altering the genome by artificially changes in genetic information and induce irreversible
changes in the function of target gene. Clustered, regularly interspaced short palindromic
repeats (CRISPR/Cas) could be a practical and straightforward approach to this disease.
CRISPR/Cas system contains Cas protein, which is controlled by a small RNA molecule to
create a double-stranded DNA gap. Evidence suggested that CRISPR/Cas was also
usable for diagnosis and treatment of SARS-CoV-2 infection. In this review study, we
discoursed on application of CRISPR technology in detection and treatment of SARSCoV-2 infection. Another aspect of this study was to introduce potential future problems in
use of CRISPR/Cas technology. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| CRISPR Technology -1.pdf | 1400/10/21 | 1199710 | دانلود |