Effect of Intravenous Administration of Tranexamic Acid During Surgery on Blood Loss in Patients with Femoral Fracture Surge
Effect of Intravenous Administration of Tranexamic Acid During Surgery on Blood Loss in Patients with Femoral Fracture Surge
نویسندگان: مسعود پریش , علیرضا صادقپور تیمور لوئی , نقی عابدینی , عطا محمودپور , سحر عالی دهستان
کلمات کلیدی: : Femoral fracture, Blood loss, Blood transfusion, Tranexamic Acid.
نشریه: 33898 , 6 , 26 , 2021
| نویسنده ثبت کننده مقاله |
نقی عابدینی |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
دانشکده پزشکی |
| کد مقاله |
77818 |
| عنوان فارسی مقاله |
Effect of Intravenous Administration of Tranexamic Acid During Surgery on Blood Loss in Patients with Femoral Fracture Surge |
| عنوان لاتین مقاله |
Effect of Intravenous Administration of Tranexamic Acid During Surgery on Blood Loss in Patients with Femoral Fracture Surge |
| ناشر |
5 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
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| Introduction: In major operations such as hip surgery, the volume of blood loss is high, and patients require blood transfusion. The current study aimed to assess the effect of Tranexamic Acid on reducing blood loss and the need for blood transfusion during and after surgery.
Methods: Assessed patients with concher femoral insertion surgery were randomly divided to intervention and control groups. After anesthesia, the intervention group received Tranexamic Acid (10 mg/kg) 15 minutes before infusion. The infusion was performed at a rate of 1 mg/kg/hr until the end of surgery. In the control group, equal volumes of normal saline were used.
Results: The mean blood loss during surgery was 1081.67±298.70 cc in the placebo group; and was 557.00±00.76 cc in the intervention group. The mean blood loss during surgery was significantly higher in the placebo group than in the intervention group (P<0.001). The mean blood loss after surgery was 427±000.7032 in the placebo group, and was 249.67±66.37 in the control group (P<0.001). Blood transfusion, during and after surgery was significantly different between the two groups (P<0.001).
Conclusion: Single dose Tranexamic Acid (10 mg/kg) 15 minutes before the infusion to patients scheduled for femoral fracture surgery can reduce blood loss and the need for blood transfusion during and after surgery. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| TM_Volume 26_Issue 6_Pages 311-316-3.pdf | 1400/10/20 | 486594 | دانلود |
| c4g60d3j2a6zj5.pdf | 1400/10/20 | 670964 | دانلود |