A comprehensive systematic review of the effectiveness of Akkermansia muciniphila, a member of the gut microbiome, for the management of obesity and associated metabolic disorders
A comprehensive systematic review of the effectiveness of Akkermansia muciniphila, a member of the gut microbiome, for the management of obesity and associated metabolic disorders
نویسندگان: ندا روشن روان , سپیده باستانی , هلدا توتونچی , بهنام کفیل قاضی جهانی , امید نیک پیام , سیمین ستوده , صمد غفاری باویل , علیرضا استاد رحیمی , نعیمه مصری علمداری
کلمات کلیدی: Akkermansia muciniphila; A.
muciniphila; gut microbiota;
weight loss obesity
نشریه: 3228 , 2021 , 2021 , 2021
| نویسنده ثبت کننده مقاله |
صمد غفاری باویل |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات قلب وعروق |
| کد مقاله |
77780 |
| عنوان فارسی مقاله |
A comprehensive systematic review of the effectiveness of Akkermansia muciniphila, a member of the gut microbiome, for the management of obesity and associated metabolic disorders |
| عنوان لاتین مقاله |
A comprehensive systematic review of the effectiveness of Akkermansia muciniphila, a member of the gut microbiome, for the management of obesity and associated metabolic disorders |
| ناشر |
10 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
خیر |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Systematic Review Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Aims and background: Obesity is recognised as a significant public health burden worldwide.
Recently the cross-talk between gut microbiota and obesity has attracted much attention. To that end,
Akkermansia muciniphila has been proposed as a promising microbe to manage obesity. In the present
systematic review, we evaluated evidence on the effectiveness and mechanisms of action of
Akkermansia muciniphila supplementation in the management of obesity.
Methods: Electronic databases of MEDLINE, PubMed, Scopus, Web of Science, and Google Scholar
were searched thought March 2020 to identify relevant published articles, and eligible articles were
systematically reviewed.
Results and conclusions: Fifteen studies were included in the present study. Findings from the present
review, which included human and animal (rodent) models support the effectiveness of
Akkermansia supplementation as a novel therapeutic approach for the management of obesity and
metabolic complications associated with obesity. However, future clinical trials are warranted to verify
these outcomes. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| Akkermansia.pdf | 1400/10/14 | 1852749 | دانلود |