چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Objective: In this study, we aimed to assess both the efficacy and tolerability of autologous conditioned serum (ACS) as an innovative wound dressing in the local management of hard-to-heal wounds. Method: In this single-blinded randomised controlled trial, patients with hard-to-heal wounds were randomly assigned to receive either ACS treatment or normal saline (NS) dressings. The treatment was applied once a week for three weeks with a final assessment at three weeks from the first ACS application. Results: A total of 30 patients took part in the study. Analysis of wound assessment data demonstrated statistically significant differences for wound surface area and Pressure Ulcer Scale for Healing scores (area score, exudate and tissue) from baseline to the end of the study in patients who received the ACS dressing, but not in patients who received the normal saline dressing. There were statistically significant differences in changes in: the wound surface area at week three (–6.4±2.69cm2 versus +0.4±2.52cm2); area score at week three (–2.2±1.08 versus +0.2±0.86); exudate at week two (–1.2±0.70 versus +0.0±0.45) and at week 3 (–1.3±0.72 versus –0.1±0.63); tissue at week two (–1.1±0.35 versus +0.0±0.53) and at week three (–1.8±0.65 versus –0.1±0.63); and the PUSH total score at week one (–1.6±0.98 versus +0.4±1.22), week two (–3.2±0.86 versus +0.4±0.98) and week three (–5.3±1.17 versus –0.0±1.33) between the ACS and NS groups, respectively. Conclusion: This trial revealed a significant decrease in wound surface area as well as a considerable improvement in wound healing in the ACS dressing group. |
| نویسنده | نفر چندم مقاله |
|---|---|
| شکیبا قلیان | اول |
| علیرضا پیش گاهی | دوم |
| سید کاظم شکوری بیلانکوهی | سوم |
| فریبا اسلامیان | چهارم |
| مهدی یوسفی | پنجم |
| شهلا دره شیری | هفتم |
| ندا دولت خواه | نهم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| JoWC_2022_31_01_000_Dolatkhah AQs[7966].pdf | 1400/11/20 | 753547 | دانلود |
