| Objectives: To compare the success rate of vital pulp therapy following complete pulpotomy in immature first
permanent molars, during caries treatment, using novel fast-setting calcium silicate cement (Novel CSC) versus
MTA.
Methods: Six- to eight- years old children, who received pulpotomy of first immatnre permanent molar using one
layer novel CSC (Protooth) or two layers slow-setting MTA (MTA Angelus) covered with glass ionomer were
recalled for radiographic and clinical evaluatfon after two years. The effects of cen1ent type, age, gender, jaw,
anesthesia type, and restoration type were assessed on the clinical success of pulpotomy and continued root
formation (apexogenesis) as the treatment outcome.
Results: Out of 366 incl11ded teeth in the st11dy, 316 teeth were available for statistical analysis. The mean
observation time was 28.2 ± 2.7 months. Novel CSC showed significantly higher clinical s11ccess rate (93.l %)
compared to MTA (84.5%). Restored teeth with stainless steel crowns after pulpotomy and treatments performed
under general anesthesia had a statistically significant effect on treatment outcome in contrast to age, gender,
and jaw type.
Conclusion: The observations of this retrospective study suggested that the success rate of vital pulp therapy
following complete pulpotomy using one layer fast-setting novel CSC was significantly higher than slow-setting
MTA covered with glass ionomer. Treatment under general anesthesia and restoration using stainless steel
crowns influenced the treatment outcome.
Clinical significance: Novel fast-setting calcium silicate cement is a promising new biomaterial for vital pulp
therapy in immature permanent molars that allows complete root formation overtime with apexogenesis. Clinicians
must also be aware of the importance of immediate definitive restoration and proper sealing and isolation
in vital pulp therapy.
Dental caries, aliliough preventable, is a chronic infectious disease
that causes healili problem worldwide. The 34.1 % prevalence of caries is
the global disease burden, which is still ilie leading cause of tooth loss
[l] . World Healili Organization (WHO) reports a range of60% to 90% of
school-aged children and nearly all adults have experienced dental
caries [2] . Deep caries lesion management in young children with
incomplete root development brings arduous challenges for dental
practitioners. Particularly, first permanent molars in children, which are
susceptible to early caries attack after |