چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Introduction: Over the last decades, there has been an increasing trend in using cell phones which are exposing us to Radio-Frequency (RF) and Extremely Low Frequency (ELF) magnetic fields with various known and unknown biological effects. This protective study aimed to investigate the impact of environmental 217 Hz (as an ELF) magnetic fields generated by mobile phones on angiogenesis as an essential factor in tumor growth, in vitro and in vivo. Material and Methods: Magnetic fields with amplitudes of 0.5, 6, 22, 44, 65 & 159 µT were exposed on Human umbilical vein endothelial cells (HUVECs) and proliferation and viability of cells were measured. 3D angiogenesis assay was done by culturing HUVEC-covered microbeads in collagen gel and counting the number of sprouting micro-vessels per microbead. The percent of CD31 positive areas in breast tumor tissues of mice was assessed in the in vivo study. Results: Results showed that some of the applied amplitudes could increase proliferation as well as the viability of HUVECs. Furthermore, 22 and 44 µT magnetic fields could significantly increase the angiogenesis of breast tumors in the mouse. Conclusion: There is a promoting effect from ELF magnetic fields generated by cell phones on the angiogenesis of tumors. It will be helpful if we recommend that cancer patients not to be exposed to cell phones. |
| نویسنده | نفر چندم مقاله |
|---|---|
| اکرم مهنا | اول |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| IJMP_Volume 18_Issue 6_Pages 421-429.pdf | 1400/09/15 | 1581838 | دانلود |
| Akhlagh.pdf | 1400/10/06 | 235043 | دانلود |
