چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | فریبا میرزائی باویل |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | مرکز تحقیقات کاربردی دارویی |
| کد مقاله | 77459 |
| عنوان فارسی مقاله | ورزش ارادی با تاثیر برمیزان پلاسمایی Retinol-binding protein 4، IGF-Binding related protein میتواند مقاومت انسولینی را در رتهای دریافت کننده رژیم پرچرب بهبود بخشد. |
| عنوان لاتین مقاله | Voluntary exercise can improve insulin resistance in rats receiving a high-fat diet by affecting the plasma levels of Retinol-binding protein 4, IGF-Binding related protein. |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | چهارمین کنگره بین المللی و 25 مین کنگره ملی فیزیولوژی و فارماکولوژی |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | |
| شهر محل برگزاری کنگره/ همایش | تهران |
| سال انتشار/ ارائه شمسی | 1400 |
| سال انتشار/ارائه میلادی | 2021 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1400/07/28 الی 1400/07/30 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://cong25.phypha.ir/ |
| آدرس علمی (Affiliation) نویسنده متقاضی | Drug applied research center, Tabriz university of medical sciences |
| نویسنده | نفر چندم مقاله |
|---|---|
| فریبا میرزائی باویل | اول |
| امین خدیوی | دوم |
| فریبا قیاسی | سوم |
| رعنا کیهان منش | چهارم |
| عنوان | متن |
|---|---|
| کلمات کلیدی | High-fat-diet, exercise, IGFBP ، RBP4 |
| خلاصه مقاله | Background and aim: Today, changes in lifestyle and diet cause a series of diseases in society. A high-fat diet can increase the chances of obesity and cardiovascular disease in addition to the development of insulin resistance in the development and progression of diabetes. Considering Retinol binding protein 4 (RBP4) produced by fat and liver cells, which can cause insulin resistance, and the relationship between IGF-binding protein (IGFBP) and the process of insulin resistance, we decided to evaluate the effect of exercise. Deliberately examine these factors and metabolic parameters. Methods: In this study, 28 male Wistar rats were randomly divided into 4 groups (n = 7). 1) Control group: without any intervention. 2) High-fat diet group: In this group, the animals received a high-fat diet for 10 weeks. 3) Voluntary exercise group: In this group, the animals did voluntary exercise for 10 weeks. 4) High-fat diet group and voluntary exercise: In this group, the animals received a high-fat diet and exercised voluntarily for 10 weeks at the same time. Voluntary exercise was performed for 10 weeks by placing the animal in a special cage with a rotating wheel. At the end of the intervention, the animals were anesthetized and blood samples were collected to measure the relevant proteins and metabolic factors (TG, HDL and cholesterol). Results: Compared with the control group, while the high-fat diet significantly increased cholesterol, triglycerides, IGFBP and RBP4 (p <0.05), exercise alone did not affect these parameters and only combined with the high-fat diet, significantly reduced them. (p <0.05).Conclusion: Conclusion: Exercise with a high-fat diet can improve insulin resistance by lowering IGFBP, RBP4, cholesterol and triglycerides. |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Dr Khadivi.JPG | 1400/09/06 | 150382 | دانلود |
| phypha25-1.pdf | 1400/09/06 | 2969077 | دانلود |
