چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Solubility and thermodynamic properties of lamotrigine as a practically insoluble drug in binary mixtures of choline chloride / propylene glycol deep eutectic solvent and water are determined by shake-flask method followed by a spectrophotometric method at the temperature range of 293.2–313.2 K. The acquired molar data are correlated to the linear and non-linear solubility models including van’t Hoff, the mixture response surface, the Jouyban-Acree, the Jouyban-Acree-van’t Hoff, the modified Wilson and the λh equations. The accuracy of each model is tested by the mean relative deviation of the back-calculated solubility data. Moreover, the apparent thermodynamic properties of lamotrigine dissolution are also calculated based on the van't Hoff and Gibbs equations. |
| نویسنده | نفر چندم مقاله |
|---|---|
| آیناز ضرغام پور | اول |
| میلاد مرادی | دوم |
| الهه رحیم پور | سوم |
| ابوالقاسم جویبان | ششم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| J Mol Liq 344 (2021) 117935.pdf | 1400/09/01 | 1194655 | دانلود |
