| COVID-19, the newly emerged viral disease spreading
with an unstoppable rate, has been in the center of
attentions all over the world. The virus causes acute
respiratory distress syndrome (ARDS) and has the most
of its victims in more vulnerable groups such as the
elderly and people with underlying diseases like diabetes
or cardiopulmonary diseased.1
Same as any other newly
emerged viral disease, there are no definite and curative
treatments available for the COVID-19 till now, so almost
all of the available therapies are designed to support the
body against the virus. The body reacts to the environment
according to its resources, and a healthy and complete
nutrition is on the top of any supportive therapies against
any kind of diseases and provides the resources to the
body’s defense mechanisms. Body systems, defensive
barriers and immune responses are all reinforced with
the fuel provided by a complete and healthy nutrition,
fighting the mighty COVID-19 is no exception. One of
the most controversial nutrients of these days is vitamin
C, claimed to have beneficial effects on COVID-19 by
some authorities and being criticized by the others on the
other hand. As it is known that sufficient vitamin C can
reinforce the body’s first defense lines (i.e. the skin, mucus
membranes, and other innate immune mechanisms)
which can effectively protect against infectious diseases.2
Vitamin C deficiency has been shown to be related to
the increased risk and severity of influenza infections.
Vitamin C supplementation has shown promising results
in the activation of the innate immune system against
influenza A virus/ H1N1 infection, and was shown to
reduce the replication cycle of the virus.There is evidence
suggesting that the intake of vitamin C can also reduce
the incidence of upper respiratory tract infection,
especially among the female population.3 Low levels of
vitamin C are common in critically ill patients due to
decreased intake and increased needs. Because vitamin
C is multifunctional, hypovitaminosis can increase the
severity of illness and hinder the recovery. There are
some case reports suggesting that high-dose vitamin C
administration can be associated with rapid resolution
of virus-induced ARDS without any final post-therapy
fibrosis. |