A Debate on Vitamin C: Supplementation on the Hotline for Critically Ill Patients with COVID-19

A Debate on Vitamin C: Supplementation on the Hotline for Critically Ill Patients with COVID-19


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نویسندگان: عطا محمودپور , سید علی شامخ , سروین سنایی اسکویی

کلمات کلیدی: Debate ,Vitamin C,COVID-19

نشریه: 951 , 3 , 11 , 2021

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نویسنده ثبت کننده مقاله سروین سنایی اسکویی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات علوم اعصاب
کد مقاله 77354
عنوان فارسی مقاله A Debate on Vitamin C: Supplementation on the Hotline for Critically Ill Patients with COVID-19
عنوان لاتین مقاله A Debate on Vitamin C: Supplementation on the Hotline for Critically Ill Patients with COVID-19
ناشر 3
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Letter to Editor
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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COVID-19, the newly emerged viral disease spreading with an unstoppable rate, has been in the center of attentions all over the world. The virus causes acute respiratory distress syndrome (ARDS) and has the most of its victims in more vulnerable groups such as the elderly and people with underlying diseases like diabetes or cardiopulmonary diseased.1 Same as any other newly emerged viral disease, there are no definite and curative treatments available for the COVID-19 till now, so almost all of the available therapies are designed to support the body against the virus. The body reacts to the environment according to its resources, and a healthy and complete nutrition is on the top of any supportive therapies against any kind of diseases and provides the resources to the body’s defense mechanisms. Body systems, defensive barriers and immune responses are all reinforced with the fuel provided by a complete and healthy nutrition, fighting the mighty COVID-19 is no exception. One of the most controversial nutrients of these days is vitamin C, claimed to have beneficial effects on COVID-19 by some authorities and being criticized by the others on the other hand. As it is known that sufficient vitamin C can reinforce the body’s first defense lines (i.e. the skin, mucus membranes, and other innate immune mechanisms) which can effectively protect against infectious diseases.2 Vitamin C deficiency has been shown to be related to the increased risk and severity of influenza infections. Vitamin C supplementation has shown promising results in the activation of the innate immune system against influenza A virus/ H1N1 infection, and was shown to reduce the replication cycle of the virus.There is evidence suggesting that the intake of vitamin C can also reduce the incidence of upper respiratory tract infection, especially among the female population.3 Low levels of vitamin C are common in critically ill patients due to decreased intake and increased needs. Because vitamin C is multifunctional, hypovitaminosis can increase the severity of illness and hinder the recovery. There are some case reports suggesting that high-dose vitamin C administration can be associated with rapid resolution of virus-induced ARDS without any final post-therapy fibrosis.

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نویسنده نفر چندم مقاله
عطا محمودپوراول
سید علی شامخدوم
سروین سنایی اسکوییسوم

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apb-11-395.pdf1401/05/31235436دانلود