چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| A new and efficient extraction procedure was proposed and used for the simultaneous extraction of four hydroxylated metabolites polycyclic aromatic hydrocarbons from urine samples. The extraction procedure was started by dissolving an organic polymer into a water-miscible organic solvent (iso-propanol) and its injection into the sample solution. The sorbent was re-precipitated in all parts of the solution as tiny particles and the analytes were adsorbed onto the sorbent. After that, the sorbent was separated and the adsorbed analytes were eluted by choline chloride: dichloroacetic acid deep eutectic solvent. The elution solvent was mixed with choline chloride-3,3-dimethyl butyric acid deep eutectic solvent and the mixture was applied in dispersive liquid–liquid microextraction procedure for more concentration of the analytes. After optimization, the method validation was followed according to International Council Harmonization guidelines and the results showed that wide linear ranges (26–500 000 ng/L) and low limits of detection (3.6–7.2 ng/L) and quantification (11–26 ng/L) were obtained. Satisfactory enrichment factors (435–475) and extraction recoveries (87–95%), and acceptable relative standard deviations (equal or less than 8.6%) were obtained. Finally, the introduced method was successfully applied for determina |
| نویسنده | نفر چندم مقاله |
|---|---|
| ابوالقاسم جویبان | اول |
| محبوب نعمتی | دوم |
| علی اکبر علیزاده نبیل | چهارم |
| محمدرضا افشار مقدم | پنجم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| JSS-HPAHs-2021-metabolinte.pdf | 1400/08/18 | 2307464 | دانلود |
