Safety and Toxicity Issues of Therapeutically Used Nanoparticles from the Oral Route
Safety and Toxicity Issues of Therapeutically Used Nanoparticles from the Oral Route
نویسندگان: فرزانه لطفی پور بناب , شهریار شاهی , افسانه فرجامی , سارا سلاطین , محمد محمودیان , سولماز ملکی دیزج
کلمات کلیدی: Oral, drug delivery, safety, toxicity, nanoparticles, nanotechnology
نشریه: 36751 , 2021 , 2021 , 2021
| نویسنده ثبت کننده مقاله |
سارا سلاطین |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات لثه و دندان |
| کد مقاله |
77293 |
| عنوان فارسی مقاله |
Safety and Toxicity Issues of Therapeutically Used Nanoparticles from the Oral Route |
| عنوان لاتین مقاله |
Safety and Toxicity Issues of Therapeutically Used Nanoparticles from the Oral Route |
| ناشر |
6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
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| نوع مقاله |
Review Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| The emerging science of nanotechnology sparked a research attention in its potential benefits in comparison to the conventional materials used. Oral products prepared via nanoparticles (NPs) have garnered great interest worldwide. They are used commonly to incorporate nutrients and provide antimicrobial activity. Formulation into NPs can offer opportunities for targeted drug delivery, improve drug stability in the harsh environment of the gastrointestinal (GI) tract, increase drug solubility and bioavailability, and provide sustained release in the GI tract. However, some issues like the management of toxicity and safe handling of NPs are still debated and should be well concerned before their application in oral preparations. This article will help the reader to understand safety issues of NPs in oral drug delivery and provides some recommendations to the use of NPs in the drug industry. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| 9322282.pdf | 1400/08/16 | 1067312 | دانلود |