چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Drug resistance is a major impediment in cancer therapy which strongly reduces the efciency of anti-cancer drugs. Exosomes are extracellular vesicles with cup or spherical shape with a size range of 40–150 nm released by eukaryotic cells that contain genetic materials, proteins, and lipids which mediate a specifc cell-to-cell communication. The potential roles of exosomes in intrinsic and acquired drug resistance have been reported in several studies. Furthermore, a line of evidence suggested that the content of exosomes released from tumor cells in biological samples may be associated with the clinical outcomes of cancer patients. In this review, we highlighted the recent studies regarding the potential roles of exosomes in tumor initiation, progression, and chemoresistance. This study suggests the possible role of exosomes for drug delivery and their contents in prognosis and resistance to chemotherapy in cancer patients. |
| نویسنده | نفر چندم مقاله |
|---|---|
| مصطفی مصطفی زاده | اول |
| ناصر صمدی | دوم |
| هومن کهربا | سوم |
| سانیا حیاتی لاله | پنجم |
| بهزاد برادران | چهارم |
| محمد نوری | ششم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Mostafazadeh.pdf | 1400/08/14 | 2219176 | دانلود |
