Cost-Effectiveness of Screening Helicobacter pylori for Gastric Cancer Prevention: a Systematic Review

Cost-Effectiveness of Screening Helicobacter pylori for Gastric Cancer Prevention: a Systematic Review


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نویسندگان: محمود یوسفی , منوچهر خوشباطن , مریم سرمستی , فرهاد خلیلی گشت رودخانی

کلمات کلیدی: Gastric cancer; Helicobacter pylori; Incremental cost-effectiveness ratio; Markov modeling; Screening strategies

نشریه: 20277 , 4 , 53 , 2022

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نویسنده ثبت کننده مقاله محمود یوسفی
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده مدیریت و اطلاع رسانی پزشکی
کد مقاله 77257
عنوان فارسی مقاله Cost-Effectiveness of Screening Helicobacter pylori for Gastric Cancer Prevention: a Systematic Review
عنوان لاتین مقاله Cost-Effectiveness of Screening Helicobacter pylori for Gastric Cancer Prevention: a Systematic Review
ناشر 4
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Systematic Review Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Globally, prevalence of Helicobacter pylori is around 50%, and it has a directly proportional relationship with gastric cancer. Screening and treatment of Helicobacter pylori could reduce gastric cancer by 35%. Drawing on the scarce resources, it is reasonable to use the most cost-effectiveness Helicobacter pylori screening procedure. The purpose of this study was to evaluate Helicobacter pylori screening techniques and to specify the efficient technique from a cost-effectiveness perspective. This systematic review was conducted via searching electronic databases including Scopus, Embase, PubMed, Web of Science, and Cochrane Reviews. Our search retrieved 904 articles, of which, 606 full-text studies have been selected after duplicate removal. Next, the 25 articles were sorted based on eligibility criteria and quality appraisal; eventually, only eight studies have been included for analysis. We reported the incremental cost-effectiveness ratio (ICER) screening compared to non-screening and different screening strategies. Eight studies were identified and retained for the final analysis. In this study, when screening techniques were compared to no-screening, serology screening techniques showed to be cost-effective. The lowest ICER calculated was US$$1230 cost per life-year gained (LYG) and US$1500 cost per quality-adjusted life-year (QALY). However, determining the optimal strategy compared to other strategies was depended on parameters such as context-specific, type of cost, threshold, and perspective, and also, it influenced by the framework of the cost-effectiveness analysis.

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نویسنده نفر چندم مقاله
محمود یوسفیچهارم
منوچهر خوشباطندوم
مریم سرمستیاول
فرهاد خلیلی گشت رودخانیسوم

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