چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| The mole fraction solubility of sulphadiazine (SD) in {Carbitol® (1) + water (2)} binary solvent mixtures at different temperatures from (278.15 to 313.15) K was determined. Solubility values were correlated with the combined nearly ideal binary solvent/Redlich-Kister, modified Wilson and Jouyban-Acree models. Preferential solvation parameters of SD by Carbitol® (δx1,3) were derived from their thermodynamic solution properties using the inverse Kirkwood-Buff integrals method. δx1,3 values are negative in water-rich mixtures but positive in Carbitol® mole fractions higher than 0.12. In the former case is conjecturable that hydrophobic hydration around non-polar groups of SD plays a relevant role in drug solvation. |
| نویسنده | نفر چندم مقاله |
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| ابوالقاسم جویبان | چهارم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Phys Chem Liq 59 (2021) 890-906.pdf | 1400/08/10 | 1399227 | دانلود |
