چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Solubility behavior of a poorly soluble drug (carvedilol) has been studied in the aqueous mixtures of a deep eutectic solvent composed of choline chloride and propylene glycol at different temperatures (293.15–313.15) K. The obtained solubility data are correlated using some of the well-known cosolvency models such as the van’t Hoff, the mixture response surface, the Yalkowsky, the Jouyban-Acree, the Jouyban-Acree-van’t Hoff, and the modified Wilson models. The accuracy of these mathematical models is investigated with the mean relative deviations of the back calculated solubility data. The apparent thermodynamic properties (i.e. Gibbs energy, enthalpy and entropy) of carvedilol in the investigated mixtures are also calculated with the van’t Hoff and Gibbs equations at Thm. |
| نویسنده | نفر چندم مقاله |
|---|---|
| طاهر صیاد | اول |
| میلاد مرادی | دوم |
| الهه رحیم پور | چهارم |
| ابوالقاسم جویبان | ششم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| J Mol Liq 342 (2021) 117537.pdf | 1400/08/09 | 787771 | دانلود |
