چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| In the current study, the sildenafil citrate solubility is investigated in (2-propanol + water) binary mix- tures at five different temperatures (293.2–313.2 K). The experimental solubility data are obtained from the shake-flask method and correlated with some linear and non-linear cosolvency models (i.e. the van’t Hoff, CNIBS/Redlich-Kister, the Jouyban-Acree, the Jouyban-Acree-van’t Hoff, the mixture response sur- face, Buchowski-Ksiazczak and the modified Wilson models). The accuracy of these cosolvency models is investigated with the mean relative deviations of the back calculated solubility data. The Gibbs energy, enthalpy and entropy as the apparent thermodynamic parameters are calculated utilizing the van’t Hoff and Gibbs equations for sildenafil citrate in the (2-propanol + water) binary mixtures at T hm (303.2 K). Moreover, the density values of sildenafil citrate are measured in the saturated mixtures and represented by the Jouyban-Acree model. |
| نویسنده | نفر چندم مقاله |
|---|---|
| کیمیا وکیلی | اول |
| هما رضائی | دوم |
| ابوالقاسم جویبان | چهارم |
| جلال حنائی | پنجم |
| الهه رحیم پور | هفتم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Journal of Molecular Liquids 344 (2021) 117915.pdf | 1400/08/08 | 691413 | دانلود |
