چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Abstract Background: Polycystic ovary syndrome (PCOS), as the most common endocrine disorder in reproductive-aged women, is characterized by oxidative stress and ovarian tissue infammation. Green tea extract (GTE) potentially pos‑ sesses therapeutic efects for PCOS because of the antioxidant and anti-infammatory compounds. This systematic review evaluates the potential roles of GTE on metabolic variables, hormone levels, and ovarian function in PCOS. Methods: A systematic review was conducted of published studies reporting the efects of GTE on PCOS. Several major databases, including PubMed, SCOPUS, and Google Scholar, were searched up from inception to April 2021. Clinical trials and animal studies that assessed the efects of GTE on PCOS were eligible for inclusion. Results: Of 314 articles found in the search, four human studies and four animal studies were included. All studies in humans showed the efects of GTE on weight loss. GTE’s efect on decreasing testosterone levels in humans and LH levels in animals were also reported. In addition, increases in FSH and progesterone levels in animal models were observed. Although GTE improved fasting blood sugar and insulin levels, the efect of GTE on infammatory param‑ eters, such as TNF-alpha and IL-6 and antioxidant status, was limited to animal studies. Conclusion: Therefore, this review suggests that GTE could be considered a potential agent to attenuate PCOS com‑ plications mainly due to its efect on weight loss and glycemic c levels. However, more studies are needed to formulate conclusions about the efects and mechanisms of GTE in PCOS. |
| نویسنده | نفر چندم مقاله |
|---|---|
| وحید ملکی | اول |
| محمد علی زاده | دهم |
| فاطمه پورتیمور فرد تبریزی | چهارم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| s12958-021-00831-z.pdf | 1401/01/24 | 1812881 | دانلود |
