Coating of betanin and carvone Co-loaded nanoliposomes with synthesized cationic inulin: A strategy for enhancing the stability and bioavailability

Coating of betanin and carvone Co-loaded nanoliposomes with synthesized cationic inulin: A strategy for enhancing the stability and bioavailability


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صفحه نخست سامانه
چکیده مقاله
چکیده مقاله
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دانشگاه علوم پزشکی تبریز
دانشگاه علوم پزشکی تبریز

نویسندگان: حامد همیشه کار

کلمات کلیدی: Surface decorationNanoliposomePhysical stabilityOxidative stabilityControlled releaseDigestion stability

نشریه: 12030 , 373 , 373 , 2022

اطلاعات کلی مقاله
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نویسنده ثبت کننده مقاله حامد همیشه کار
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه مرکز تحقیقات کاربردی دارویی
کد مقاله 77184
عنوان فارسی مقاله Coating of betanin and carvone Co-loaded nanoliposomes with synthesized cationic inulin: A strategy for enhancing the stability and bioavailability
عنوان لاتین مقاله Coating of betanin and carvone Co-loaded nanoliposomes with synthesized cationic inulin: A strategy for enhancing the stability and bioavailability
ناشر 5
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ خیر
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Betanin (BET) and carvone (CAR) as antioxidant and antibacterial compounds were co-loaded in the coated nanoliposomes (NLPs) with cationic inulin to improve their stability and bioavailability. A cationic inulin was successfully synthesized and used for surface coating of the NLPs. The zeta potential, particle size, and PDI values of the coated NLPs were 21.70 ± 7.00 mV, 143.5 ± 15.2 nm, and 0.35 ± 0.03 respectively. The encapsulation efficiency values of the coated NLPs for BE and CAR were 86.1 ± 3.9 and 77.2 ± 5.2 %, respectively. Electron microscopy results showed that the coated NLPs had spherical and core–shell structures. The slowest sustained release profile in the simulated gastrointestinal condition was obtained for the coated NLPs. The physical and oxidative stability of NLPs, as well as the physical stability of loaded compounds were improved by surface coating. In conclusion, the developed nanocarrier is a suitable platform to use all benefits of BET and CAR in the food industry.

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نویسنده نفر چندم مقاله
حامد همیشه کارسوم

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Coating of betanin and carvone bioavailability.pdf1400/08/064001100دانلود