چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده | نفر چندم مقاله |
|---|---|
| فاطمه طباطبایی | اول |
| عنوان | متن |
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| خلاصه مقاله | Comparison of Medical Treatment in Adenomyosis and Uterine Myomas Fatemeh Tabatabaei 1) Department of Obstetrics and Gynecology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. 2) Department of Gynecologic Laparoscopic Surgeries, Women's Reproductive Health Research Center, Al-Zahra Hospital, Tabriz, Iran. Levonorgestrel (LNG)-releasing intrauterine device (IUD) is the preferred medical treatment for adenomyosis, due to its direct action on the uterus, low systemic levels of steroid hormones, and long-acting user-independent administration. The LNG IUD has been shown to improve adenomyosis-associated heavy menstrual bleeding and dysmenorrhea. There are little data on the efficacy of oral contraceptives specifically for adenomyosis. Concomitant use of both combined oral contraceptives and the LNG IUD was no more effective for reducing pain and bleeding than use of the LNG IUD alone. Daily administration of oral dienogest, gonadotropin-releasing hormone (GnRH) analogs and aromatase inhibitors are other hormonal therapeutic options. When hormonal medications are discontinued, enlargement of the uterus and recurrence of symptoms are usually documented within six months after discontinuation. Medical treatment of uterine fibroids varies depending on the clinical signs of fibroids and the patient's desire for fertility. Heavy menstrual bleeding, pain and bulk symptoms are the most common symptoms in need of treatment. Combined estrogen-progestin contraceptives (oral contraceptive pills, vaginal ring, or transdermal patch), progestin-releasing intrauterine devices and tranexamic acid are the most common medical therapy utilized by patients with HMB and fibroids. GnRH analogs, including antagonists and agonists, can also reduce HMB. GnRH analogs also reduce fibroid volume but have potential adverse effects that limit use. Patients desire for fertility will generally require surgical approaches instead of medical treatment. Progesterone receptor modulators (UPA), androgenic compounds (danazol), aromatase inhibitors (letrozol), selective estrogen reuptake modulators (raloxifene), complementary medicine (herbal supplements & acupuncture) are no longer recommended today. |
| کلمات کلیدی | Myoma, Adenomyosis, Medical treatment |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
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| 1.png | 1400/07/28 | 211445 | دانلود |
| 2.png | 1400/07/28 | 124283 | دانلود |
| Certificate14000.pdf | 1400/08/09 | 117300 | دانلود |
