چاپ صفحه |  صفحه نخست سامانه |  نویسندگان |  اطلاعات تفضیلی |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| نویسنده ثبت کننده مقاله | امیر فتاحی |
| مرحله جاری مقاله | تایید نهایی |
| دانشکده/مرکز مربوطه | دانشکده علوم نوین پزشکی |
| کد مقاله | 77047 |
| عنوان فارسی مقاله | Follicular Fluid Plgf/Sflt 1 Ratio And Soluble Receptor for Advanced Glycation End–Products Correlate With Ovarian Sensitivity Index In Women Undergoing A.R.T. |
| عنوان لاتین مقاله | Follicular Fluid Plgf/Sflt 1 Ratio And Soluble Receptor for Advanced Glycation End–Products Correlate With Ovarian Sensitivity Index In Women Undergoing A.R.T. |
| نوع ارائه | پوستر |
| عنوان کنگره / همایش | The 4th International Congress on Reproduction (ISERB 2018) |
| نوع کنگره / همایش | بین المللی |
| کشور محل برگزاری کنگره/ همایش | Iran (Islamic Republic) |
| شهر محل برگزاری کنگره/ همایش | تهران |
| سال انتشار/ ارائه شمسی | 1397 |
| سال انتشار/ارائه میلادی | 2018 |
| تاریخ شمسی شروع و خاتمه کنگره/همایش | 1397/02/05 الی 1397/02/07 |
| آدرس لینک مقاله/ همایش در شبکه اینترنت | https://www.en.symposia.ir/ISERB04 |
| آدرس علمی (Affiliation) نویسنده متقاضی | Department of Reproductive Biology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences |
| نویسنده | نفر چندم مقاله |
|---|---|
| امیر فتاحی | اول |
| حمیدرضا نجابتی | دوم |
| زینب لطیفی | سوم |
| علی مطاع | چهارم |
| لعیا فرزدی | پنجم |
| مرتضی قوجازاده | ششم |
| کبری حمدی | هفتم |
| محمد نوری | هشتم |
| پروین حکیمی | نهم |
| عنوان | متن |
|---|---|
| خلاصه مقاله | Background: Considering potential roles of soluble receptor for advanced glycation end products (sRAGE) and placental growth factor (PlGF) in ovarian function and embryoimplantation, in the present study we have evaluated the association of these factors and also PlGF/sFlt-1 ratio with the ovarian response and implantation rate by dividing patients according to the OSI. Methods: In a cross-sectional study, 90 infertile women who were undergoing ICSI cycle using long protocol were recruited. The patients weredivided according to ovarian sensitivity index (OSI). ICSI cycle outcomes were evaluated for each patient and PlGF, sFlt-1 and sRAGE levels of follicular fluid were assayed using commercial ELISA kits. Results: Follicular fluid (FF) sRAGE levels and PlGF/sFlt-1 ratio were statistically greater in high‑responder women than other responders (p <0.05). Positive correlations were obtained between sRAGE level with the number of oocytes, follicles and OSI level. sRAGE levels with a cutoff value of 4.83 (ng/ml) for evaluating the pregnancy outcome showed 81.8 % sensitivity and 60.7 % specificity. Furthermore, there were positive associations between PlGF/sFlt-1 ratio with thenumber of oocytes, embryos and OSI level. Conclusion: In conclusion, the results of the current study supported that good ovarian response is independent of pregnancy outcome. Our results showed that FF levels of sRAGE and PlGF/sFlt-1 ratio could be used as markers for determining the high-responder women. Also, FF sRAGE levels could be a good predictor of ART outcome. |
| کلمات کلیدی | Ovarian Response ، Soluble Receptor for Advanced Glycation End Products ، Placental Growth Factor ، Embryo Implantation ، ICSI Cycle |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| Tehran 2018 2 (Abstract).pdf | 1400/07/22 | 3150069 | دانلود |
| Govahi 2018.jpg | 1400/07/22 | 593793 | دانلود |
