The Effect of Antenatal Betamethasone on Prevention of Neonatal Respiratory Distress Syndrome before Elective Cesarean Section at Term

The Effect of Antenatal Betamethasone on Prevention of Neonatal Respiratory Distress Syndrome before Elective Cesarean Section at Term


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دانشگاه علوم پزشکی تبریز
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نویسندگان: فرناز صحاف ابراهیمی , ناهیده افشار زکریا

کلمات کلیدی: Keywords: Betamethasone, cesarean section, elective, respiratory distress syndrome

نشریه: 42234 , 4 , 10 , 2021

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نویسنده ثبت کننده مقاله ناهیده افشار زکریا
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه دانشکده پزشکی ,سلامت باروری زنان
کد مقاله 76936
عنوان فارسی مقاله The Effect of Antenatal Betamethasone on Prevention of Neonatal Respiratory Distress Syndrome before Elective Cesarean Section at Term
عنوان لاتین مقاله The Effect of Antenatal Betamethasone on Prevention of Neonatal Respiratory Distress Syndrome before Elective Cesarean Section at Term
ناشر 2
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Background: Respiratory distress syndrome (RDS) is an important respiratory disease possibly caused by surfactant deficiency in infants and has a heavy financial burden on the country's health system. The purpose of the present study was to evaluate the relationship between RDS in neonates who were born by elective cesarean at term with and without corticosteroids. Materials and Methods: This randomized clinical trial study was performed on all mothers who delivered by elective cesarean section at Alzahra and Taleghani Hospital with a Pregnancy age of more than 37 weeks. After considering exclusion criteria, the patients were randomly divided into either betamethasone (IM injection of 12 mg daily for two doses) or the control group. The comparison of these two groups was in RDS, hospitalization in the neonatal ward, or admission to newborn intensive care unit (NICU). Results: One hundred and sixty patients participated in the study. Fifty percentage (n = 80) of them received betamethasone and 50% did not. Of all, 160 neonates, 73.8% in Group 1 and 82.5 of the Group 2 had a 1st-min Apgar score of 9.9–9.10. Significant differences were observed in neonatal Apgar score in two groups (P < 0.05). RDS was found in 11 (6.87%) neonates born from both groups. The hospitalization of neonatal in intensive care units and the time of hospitalization of infants in the betamethasone group were less than the control group and statistically significant (P < 0.05). No cases of necrotizing enterocolitis and neonatal sepsis were observed. Conclusion: The results of the present study represented that giving betamethasone to mothers with programmed elective cesarean at term beseem to have a beneficial effect on RDS, NICU admission, and hospitalization. More studies with a larger sample size including the effects of other steroids are recommended. Keywords: Betamethasone, cesarean section, elective, respiratory distress syndrome

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نویسنده نفر چندم مقاله
فرناز صحاف ابراهیمیاول
ناهیده افشار زکریادوم

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