Determinants of health-related quality of life in patients with celiac disease: a structural equation modeling

Determinants of health-related quality of life in patients with celiac disease: a structural equation modeling


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نویسندگان: زینب نیک نیاز , لیلا نیک نیاز , مهدیه عباسعلیزاد فرهنگی , محمد اصغری جعفرآبادی , مسعود شیرمحمدی

کلمات کلیدی: Coeliac disease, Quality of life, Structural equation modeling

نشریه: 13468 , 204 , 19 , 2021

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نویسنده ثبت کننده مقاله لیلا نیک نیاز
مرحله جاری مقاله تایید نهایی
دانشکده/مرکز مربوطه بیماری های گوارش و کبد
کد مقاله 76782
عنوان فارسی مقاله Determinants of health-related quality of life in patients with celiac disease: a structural equation modeling
عنوان لاتین مقاله Determinants of health-related quality of life in patients with celiac disease: a structural equation modeling
ناشر 5
آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ بلی
عنوان نشریه (خارج از لیست فوق)
نوع مقاله Original Article
نحوه ایندکس شدن مقاله ایندکس شده سطح یک – ISI - Web of Science
آدرس لینک مقاله/ همایش در شبکه اینترنت

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Background: We aimed to investigate the determinants of Health-related quality of life (HRQOL) in Iranian patients with celiac disease (CD) using the structural equation modeling (SEM). Methods: In the present cross-sectional study, a total of 170 adult patients with CD were recruited. The information regarding adherence to diet, symptom severity, and HRQOL were collected using the celiac disease adherence test (CDAT), gastrointestinal symptom rating scale (GSRS), and SF-36 questionnaire respectively. Association between various studied variables and HRQOL was assessed using SEM. The standardized regression weights were used to assess total, direct and indirect efects. The model ft indices were used to assess the “goodness of ft” between the hypothesized models. Results: The mean age of participants was 37.57±9.59 years. The results of SEM indicated that the overall ft of our model was acceptable. Adherence to the diet, GSRS score, occupation, and education level was signifcantly related to PCS of SF-36; and adherence to the diet, GSRS score, and education level were signifcantly correlated with MCS of SF-36. The analysis of indirect associations indicated that only adherence to diet indirectly via GSRS score was signifcantly associated with PCS and MCS of SF-36. Conclusion: In adult patients with celiac disease, HRQOL was associated with age, education, adherence to GFD, and GSRS score. Additionally, occupation and disease duration were associated with HRQOL only in women and men respectively.

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نویسنده نفر چندم مقاله
زینب نیک نیازاول
لیلا نیک نیازپنجم
مهدیه عباسعلیزاد فرهنگیسوم
محمد اصغری جعفرآبادیدوم
مسعود شیرمحمدیچهارم

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