| خلاصه مقاله | The misdiagnosis of cerebellar infarctions is important with regard to both treatment and prognosis.
Many articles concentrate
on infarcts that mimic peripheral vestibulopathies. However, the patients with cerebellar strokes are
also misdiagnosed with migraines, toxic encephalopathies, and gastritis or gastroenteritis. The studies
report three major pitfalls.
The first pitfall involves the clinical evaluation. Half of the patients in a study were young and
without vascular risk factors, which may have lessened clinical suspicion. Also, there was a failure to
recognize the spectrum of presenting symptoms that should arouse suspicion for an acute cerebellar
stroke, including headache, gait unsteadiness, vertigo, vomiting, and slurred speech. Vomiting in the
absence of other gastrointestinal symptoms, especially diarrhea, should raise the possibility of a
neurologic cause. Most patients had additional visual, sensory, or oculomotor symptoms often
involving localized body parts that suggest a focal brain process. An incompletely performed or
documented neurologic examination, especially examination of eye movements, coordination, and
gait5 are often the culprit.
The second pitfall concerns diagnostic testing. In particular, a normal CT scan does not exclude
ischemic stroke in general and poorly visualizes the posterior fossa because of bony artifacts. The
findings on CT scan are often normal in the acute stages of cerebellar infarction. An MR diffusion-
weighted imaging sequence (DWI) is the most sensitive test for the detection of acute ischemic
stroke. However, DWI does not always reveal an acute infarction, and its sensitivity is slightly lower
in the posterior circulation. A common mechanism of cerebellar stroke in young patients is
extracranial vertebral artery dissection. Failure to identify and treat these lesions may lead to further
embolization and infarctions; survivors of cerebellar stroke have been shown to develop subsequent
brain stem infarction. Cardioembolism is another important consideration.
The third category of pitfalls is related to establishing a diagnosis. A failure to arrive at a specific
diagnosis that completely explains the symptoms, signs, and imaging results is a common pitfall.
Some patients may present with headache, and may be misdiagnosed with complicated migraine.
Given the high prevalence of migraine in young adults, it is not surprising that clinicians make this
error.
Many of the misdiagnosed patients will have poor outcomes. Cerebellar stroke can progress from
seemingly benign symptoms
such as nausea, vomiting, dizziness, and headache to serious neurologic impairment due to additional
infarcts, hydrocephalus, mass effect from edema formation, and brain stem compression. |