pH-induced homogeneous liquid–liquid microextraction method based on new switchable deep eutectic solvent for the extraction of three antiepileptic drugs from breast milk
pH-induced homogeneous liquid–liquid microextraction method based on new switchable deep eutectic solvent for the extraction of three antiepileptic drugs from breast milk
نویسندگان: الناز مرزی خسروشاهی , ابوالقاسم جویبان , محمدرضا افشار مقدم , محبوب نعمتی
کلمات کلیدی: antiepileptic drugsbreast milkdeep eutectic solventgas chromatographyhomogeneous liquid-liquid microextraction
نشریه: 4463 , 14 , 13 , 2021
| نویسنده ثبت کننده مقاله |
محمدرضا افشار مقدم |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات ایمنی غذا و دارو |
| کد مقاله |
76522 |
| عنوان فارسی مقاله |
pH-induced homogeneous liquid–liquid microextraction method based on new switchable deep eutectic solvent for the extraction of three antiepileptic drugs from breast milk |
| عنوان لاتین مقاله |
pH-induced homogeneous liquid–liquid microextraction method based on new switchable deep eutectic solvent for the extraction of three antiepileptic drugs from breast milk |
| ناشر |
6 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Original Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Aim: A pH-induced homogeneous liquid–liquid microextraction (HLLME) using a new switchable deep eutectic solvent has been used for the extraction of three antiepileptic drugs from breast milk samples. Methodology: This method is based on phase separation by changing pH. An ammonia solution and a phosphocholine chloride: hexanoic acid: p-aminophenol deep eutectic solvents were used as the phase separation agent and extraction solvent, respectively. Results: Significant factors were studied and the detection limits and enrichment factors were in the ranges of 0.009–0.19 ng ml-1 and 182–212 for the analytes, respectively. Also, linear ranges were wide (0.63–500 ng ml-1) and the method precision was acceptable. Conclusion: The introduced method was successfully applied for the determination of the analyte concentrations in breast milk samples. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| bio-2021-0067.pdf | 1400/06/16 | 932931 | دانلود |