چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| The solubility profile of ketoconazole (KTZ) in the binary mixtures of N-methyl-2-pyrrolidone and ethanol is determined by a shake-flask method followed by a spectrophotometry method in the temperature range of 293.2–313.2 K. The obtained solubility values of KTZ are correlated using some linear and non-linear cosolvency models. Moreover, the density of saturated mixtures is also represented by the Jouyban-Acree model at different temperatures. The accuracy of each used model is investigated by the mean relative deviations (MRD %) of the back-calculated solubility and density data. The apparent thermodynamic properties of KTZ dissolution are also computed based on the van't Hoff and Gibbs equations. |
| نویسنده | نفر چندم مقاله |
|---|---|
| میلاد مرادی | اول |
| الهه رحیم پور | دوم |
| ابوالقاسم جویبان | پنجم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| J Mol Liq 326 (2021) 115287.pdf | 1400/05/11 | 720217 | دانلود |
