Targeting Mitochondrial Biogenesis with Polyphenol Compounds
Targeting Mitochondrial Biogenesis with Polyphenol Compounds
نویسندگان: مهدیه علیپور , سپیده زنونی واحد , سید مهدی حسینی یان خطیبی , الهام احمدیان , محمد رضا اردلان
کلمات کلیدی: Cell signaling, Mitochondria, Pharmacology, Phytomedicine, Sirtuins
نشریه: 55421 , 4946711 , 2021 , 2021
| نویسنده ثبت کننده مقاله |
الهام احمدیان |
| مرحله جاری مقاله |
تایید نهایی |
| دانشکده/مرکز مربوطه |
مرکز تحقیقات کلیه |
| کد مقاله |
76446 |
| عنوان فارسی مقاله |
Targeting Mitochondrial Biogenesis with Polyphenol Compounds |
| عنوان لاتین مقاله |
Targeting Mitochondrial Biogenesis with Polyphenol Compounds |
| ناشر |
9 |
| آیا مقاله از طرح تحقیقاتی و یا منتورشیپ استخراج شده است؟ |
بلی |
| عنوان نشریه (خارج از لیست فوق) |
|
| نوع مقاله |
Review Article |
| نحوه ایندکس شدن مقاله |
ایندکس شده سطح یک – ISI - Web of Science |
| آدرس لینک مقاله/ همایش در شبکه اینترنت |
|
| Appropriate mitochondrial physiology is an essential for health and survival. Cells have developed unique mechanisms to adapt to stress circumstances and changes in metabolic demands, by meditating mitochondrial function and number. In this context, sufficient mitochondrial biogenesis is necessary for efficient cell function and haemostasis, which is dependent on the regulation of ATP generation and maintenance of mitochondrial DNA (mtDNA). These procedures play a primary role in the processes of inflammation, aging, cancer, metabolic diseases, and neurodegeneration. Polyphenols have been considered as the main components of plants, fruits, and natural extracts with proven therapeutic effects during the time. These components regulate the intracellular pathways of mitochondrial biogenesis. Therefore, the current review is aimed at representing an updated review which determines the effects of different natural polyphenol compounds from various plant kingdoms on modulating signaling pathways of mitochondrial biogenesis that could be a promising alternative for the treatment of several disorders. |
| نام فایل |
تاریخ درج فایل |
اندازه فایل |
دانلود |
| 4946711.pdf | 1400/05/11 | 2147050 | دانلود |