چاپ صفحه |  صفحه نخست سامانه |  چکیده مقاله |  نویسندگان |  دانلود مقاله | دانشگاه علوم پزشکی تبریز |
| Statement of the Problem: Traditional clinical criteria are usually not sufficient for determin- ing the sites of active periodontal disease, monitoring the response to treatment, or measuring the susceptibility to future disease development. Past studies have shown that heat shock pro- tein 70 (HSP70) are involved in the etiology of periodontal disease. Purpose: The aim of this study was to evaluate the level of HSP70 in saliva of patients with chronic periodontitis (CP). Materials and Method: In our case-control study, the saliva samples of 45 patients with CP and 45 age- and sex-matched healthy subjects were collected. Salivary HSP70 was measured by enzyme-linked immunosorbent assay method. The results were analyzed by statistical tests using SPSS 16 and the statistically significant difference was set at p< 0.05. Results: In this study, the mean salivary HSP70 level was 2.81±0.61ng/ml in the patient group and 1.96±0.77ng/ml in the healthy group, with a significant difference (p< 0.05).In addition, the results of spearman correlation analysis showed a positive correlation between salivary HSP 70 and clinical periodontal index. Conclusion: The results of this study showed that the salivary HSP70 level in patients with CP is higher than that in healthy subjects. As a result, salivary HSP70 might be considered as a marker in the pathogenesis of CP. |
| نویسنده | نفر چندم مقاله |
|---|---|
| پریا مطهری | اول |
| حامد جباروند بهروز | سوم |
| سولماز پور زارع مهربانی | دوم |
| نام فایل | تاریخ درج فایل | اندازه فایل | دانلود |
|---|---|---|---|
| IMG-20210801-WA0001.jpg | 1400/05/12 | 80523 | دانلود |
| IMG-20210801-WA0000.jpg | 1400/05/12 | 77853 | دانلود |
| Acceptance-letter.pdf | 1400/05/12 | 205664 | دانلود |
| U4- 871548-Motahari.pdf | 1400/05/06 | 150126 | دانلود |
